Professor Elof Carlson
Biology 150
Spring 2000

Questions: units one and two

To give you an idea of the format of the examinations for units one and two I include questions in three formats: multiple choice, definitions, and multi-part essays. Each of the two examinations for these units will consist of such questions. Details of the examination and what to study will be announced in class.

  1. Who was responsible for formalizing the theory of inheritance of acquired characteristics?
    1. H. J. Muller
    2. A. C. Kinsey
    3. J. B. Lamarck
    4. G. Mendel
    5. M. Schleiden

  2. The term soma refers to
    1. the embryonic rudiment that forms the clitoris
    2. the cells of an organism that are not the reproductive tissue
    3. the state of an allele when it is dominant
    4. the cells of an organism that form sperm and eggs
    5. the region of a chromosome to which a spindle fiber is attached

  3. If the parents in a cross are Rr male x Rr female, what percent of the offspring will be Rr?
    1. zero
    2. 0.75
    3. 0.25
    4. 0.67
    5. 0.50

  4. If the healthy parents of a child with cystic fibrosis have another pregnancy, the chances that this child will not have symptoms of cystic fibrosis will be
    1. 0.75
    2. 0.50
    3. 0.25
    4. 0.67
    5. 0.33

  5. In a cross of the genotypes GG x Gg, what percent of the offspring will be (g)?
    1. zero
    2. 0.75
    3. 0.67
    4. 0.50
    5. 0.25

  6. Huntington disease is a dominant autosomal disorder. A man who has inherited the gene for Huntington disease marries a woman who is homozygous for the normal allele. Their first child, a daughter, is born. What is the probability that she is homozygous for the recessive allele?
    1. zero
    2. 0.25
    3. 0.33
    4. 0.75
    5. 0.50

  7. A male is red-green color deficient. His parents have normal color vision. The genotype of his father, where R= normal color vision and r = color deficient vision, is
    1. Rr
    2. rY
    3. RY
    4. rr
    5. RR

  8. Which one of the following terms represents the phenotype of a child with cystic fibrosis
    1. (f)
    2. ff
    3. Ff
    4. (F)
    5. FF

  9. In a cross of Aa Bb x Aa bb, what portion of the offspring will be aa bb?
    1. one sixteenth
    2. one fourth
    3. one half
    4. one eighth
    5. three fourths

  10. Factor VIII hemophilia (h) is a X-linked trait. If the parents clot normally, this boy's genotype is
    1. HY
    2. hh
    3. Hh
    4. hY
    5. HH

  11. Humans traits involving many genes produce all except which one of the following conditions
    1. human height
    2. human skin color
    3. time of onset of a hereditary trait
    4. variation in chromosome number
    5. variation in severity of a monogenic trait

  12. What are the chances that if no crossing over or new mutation occurs, that one of your eggs or sperm will be identical in genotype to the egg or sperm that produced you
    1. one in 24
    2. one in 4
    3. one in 9 million
    4. one in 46
    5. one in 1000

  13. How would one represent a female with a normal human chromosome number
    1. 46,XY
    2. 44,XY
    3. 44.XX
    4. 46,XX
    5. 23,X

  14. Which one of the following is derived from the wolffian duct?
    1. penile glans
    2. uterus
    3. seminiferous tubules
    4. scrotum
    5. epididymis

  15. Which one of the following is derived from the mullerian duct?
    1. vas deferens
    2. upper vagina
    3. penile shaft
    4. labia minora
    5. graafian follicle

  16. Which structure in the female corresponds (is homologous) to the penile shaft?
    1. the labia minora
    2. the labia majora
    3. the clitoris
    4. the uterus
    5. the oviducts

  17. A sperm has a mutation in its Y chromosome that makes the SRY gene non-functional. The resulting child of this fertilization will be
    1. a male with sterile testes
    2. a female with sterile ovaries that produce no steroid hormones
    3. a male pseudohermaphrodite
    4. a female pseudohermaphrodite
    5. a true hermaphrodite

  18. A zygote that is 46,XX has a homozygous recessive gene that prevents the adrenal gland from producing cortisol. The child at birth is most likely to have:
    1. penis scrotum, testes, uterus, oviducts, upper vagina
    2. penis, bifid scrotum, vagina, uterus, oviducts, ovaries
    3. lower vagina, labia minora and majora, clitoris, testes
    4. penis and vagina, sperm transport system, uterus, oviducts, and ovotestes
    5. normal female appearance in all respects

  19. Two zygotes, one 46,XY and the other 46,XX collide in the oviduct and fuse. The resulting infant is most likely to have
    1. male pseudohermaphroditism
    2. female pseudohermaphroditism
    3. congenital adrenal hyperplasia
    4. true hermaphroditism due to chimerism
    5. Klinefelter syndrome

  20. The term menarche refers to
    1. the cessation of all menstrual periods at age 50
    2. the first period a woman experiences
    3. paraphilia
    4. the average homosexual activity in a Kinsey scale
    5. the development of pubic hair at puberty

  21. Which one of the following is a female pseudohermaphrodite
    1. congenital insensitivity to testosterone
    2. congenital insensitivity to MIS
    3. congenital adrenal hyperplasia
    4. Turner syndrome
    5. Klinefelter syndrome

  22. What is the Kinsey scale applied to?
    1. rate of appearance of pubic hair
    2. age at which menopause begins
    3. frequency of ovulation per month
    4. frequency of sexual intercourse per week
    5. percent of homosexual activity in a lifetime

  23. Which one of the following is a paraphilia?
    1. having ovarian and testicular tissue
    2. having sex with a person of the same sex
    3. getting sexually aroused only when looking at photographs in Playboy
    4. masturbation
    5. spouse abuse

  24. What percent of males primarily have their sexual outlet with other males?
    1. less than 1in 100
    2. 2 to 10
    3. 40
    4. less than 1 in 1000
    5. 20

  25. Which of the seven sexes of humans is used to determine one's sex on a birth certificate?
    1. external genital sex
    2. gonadal sex
    3. chromosomal sex
    4. genetic sex
    5. internal genital sex

Definitions
Using complete sentences and the space provided define each of the following terms.

  1. Lamarckism
  2. ethnic disorders
  3. the gene as the basis of life
  4. dominant trait
  5. heterozygous genotype
  6. pedigree analysis
  7. chromosome theory of heredity
  8. SRY gene
  9. male pseudohermaphrodite
  10. chimera

Multi-part essays

  1. For each of the following syndromes discuss the fate of a) the neutral gonad; b) wolffian ducts; c) mullerian ducts, and d) external genital rudiments.

    1. Klinefelter syndrome
      1. neutral gonad
      2. wolffian ducts
      3. mullerian ducts
      4. external genital rudiments

    2. Congenital adrenal hyperplasia syndrome
      1. neutral gonad
      2. wolffian ducts
      3. mullerian ducts
      4. external genital rudiments

    3. Congenital insensitivity to mullerian inhibiting substance
      1. neutral gonad
      2. wolffian ducts
      3. mullerian ducts
      4. external genital rudiments

    4. XY female
      1. neutral gonad
      2. wolffian ducts
      3. mullerian ducts
      4. external genital rudiments

  2. The parents of a child with albinism (a) both have normal pigmentation (A). They wish to have another child and seek advice from a genetic counselor. Answer the following questions about this counseling session. [the symbols (a) and (A) are the phenotypes in question].

    1. What is the genotype of their albino child?
    2. what is the genotype of the father of that child?
    3. what is the genotype of mother of that child?
    4. what is the probability that their next child will be an albino in phenotype?
    5. what is the probability, if their next child is normal in phenotype, that that child is heterozygous in genotype?

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Last modified January 24, 2000
BIO 150 - Practice Exam: Units I & II / Michael S. Rosenberg